Leep Procedure - Studies and Links

Leep Procedure - Studies and Links

• University OB-Gyn - Information with Pictures on LEEP Procedures

• Eyes on the Prize - FAQ about LEEP procedures

• MY Doc - Basic information for LEEP procedures

• Family Practice - Article by John L. Pfenninger, MD on LEEP vs. Cryotherapy

• MSN Health - A lot of general information on LEEPs

• Women's Diagnostic Cyber - A doctors response to a woman's question about HGSIL, LEEPs, and Cervical cancer.

• Mederm - Information on LEEP procedure from the American College Obstetricians and Gynecologists.

• Family Planning - Information on preparing for a LEEP, the procedure, results of a LEEP, complications, and post-operative instructions.

• University of Montana - Risks and Advantages of LEEP procedure

• Sunnybrook Health Science Centre

• Cleveland Health Clinic - "Understanding the LEEP Procedure", and article with pictures

Leep Procedures - Studies on LEEP Procedures

Mathevet P, Chemali E, Roy M, Dargent D. Eur J Obstet Gynecol Reprod Biol. 2003 Feb 10;106(2):214-8.

Department of Gynecology, Hopital Edouard Herriot, Pavillon L, Place d'Arsonval, 69437 Cedex 03, Lyon, France

OBJECTIVE: To evaluate the long-term recurrence rates and complication of different techniques of cervical ablation. METHODS: A randomized trial of three techniques of conization (cold knife, laser, and loop electrosurgical excisional procedure (LEEP)) for cervical intraepithelial neoplasia (CIN) in which 110 patients had been recruited. RESULTS: Eighty-six patients were followed-up for more than 3 years. Of these 28 had been treated with the cold knife, 29 with LEEP and 29 by laser. Five recurrences were observed, one in the cold knife group, two in the LEEP group and two in the laser group (P=NS). The only observed complication was cervical stenosis: zero cases in the laser group, one case in the LEEP group and four cases in the cold knife group (laser versus cold knife: P=0.03; LEEP versus cold knife: P=0.06). Fifty pregnancies were observed in 39 patients. First and second trimester outcomes of pregnancy were without complications. One patient treated with the LEEP presented with a premature rupture of membranes and premature labor at 36 weeks. A total of nine cesarean sections were performed with two cases for cervical dystocia.

CONCLUSION: There is no major difference in obstetrical outcome between the three techniques.

Pub Med

Leep Procedures - Risk factors for early cytologic abnormalities after loop electrosurgical excision procedure.

OBJECTIVE: To evaluate risk factors for early cytologic abnormalities and recurrent cervical dysplasia after loop electrosurgical excision procedure (LEEP). METHODS: A retrospective analysis was performed of all pathology records for LEEPs performed at our institution from January 1996 through July 1998. Follow-up cytology from 2 through 12 months after LEEP was reviewed. Patients with abnormal cytology were referred for further colposcopic evaluation. Statistical analysis using chi2 test for trend, proportional hazards model test, Fisher exact tests, and life table analysis were performed to identify risk factors for early cytologic abnormalities after LEEP and to determine relative risk of recurrent dysplasia. RESULTS: A total of 298 women underwent LEEP during the study period, and 29% of these had cytologic abnormalities after LEEP. Grade of dysplasia, ectocervical marginal status, endocervical marginal status, and glandular involvement with dysplasia were not found to be independent risk factors for early cytologic abnormalities. However, when risk factors were analyzed cumulatively, the abnormal cytology rate increased from 24% with no risk factors to 67% with three risk factors present (P =.037). Of patients with abnormal cytology after LEEP, 40% developed subsequent dysplasia, and the mean time to diagnosis was approximately 6 months. The relative risk of subsequent dysplasia ranged from a 20% increase to twice the risk if post-LEEP cytology was low-grade squamous intraepithelial lesion or high-grade squamous intraepithelial lesion, respectively.

CONCLUSION: Based on these results, consideration should be given for early colposcopic examination of patients who have evidence of marginal involvement or endocervical glandular involvement with dysplasia. These patients are at increased risk for abnormal cytology and recurrent dysplasia. This initial visit should occur at 6 months, as the mean time to recurrence of dysplasia was 6.5 months.

Pub Med

Leep Procedures - Loop electrosurgical excision procedure: a valuable method for the treatment of cervical intraepithelial neoplasia

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Science, Beijing 100730, China.

OBJECTIVE: To determine the effectiveness and safety of loop electrosurgical excision procedure (LEEP) for the management of cervical intraepithelial neoplasia (CIN) and the significance of positive margins in cervical cone biopsy specimens with the relationship of prognosis. METHODS: LEEP under local anesthesia and colposcopic guidance was performed in an outpatient of colposcopic clinic. Records of 135 patients treated between Feb 1992 and Jul 1999 were reviewed prospectively. RESULTS: The median age of patients in this study was 42 years (range 18-67 years), parity 2.2 times (range 0-8 times). High-grade squamous intraepithelial lesion (HGSIL) accounted for majority of diagnosis according to pap smear (65.9%) and colposcopy (75.6%) respectively. The results of LEEP demonstrated negative histology in 7 patients (5.2%), human papilloma virus (HPV) infection in 2 patients (1.5%), CINI in 15 patients (11.1%), HGSIL in 108 patients (80.0%) which including 20 patients (14.8%) of CINII, 88 patients (65.2%) of CINIII, microinvasion in 3 patients (2.2%). Clear resection margin of lesion in cervix was noted in 78 (57.8%) patients. Unclear margins were appeared in 57 (42.2%) patients including 21 cases (15.6%) of resection margin positive and 36 cases(26.7%) of resection margin undetermined. HGSIL accounted for the majority (54 cases, 94.7%) in this kind of patients. The residual CIN occurred in 1 patient (4.8%) with the resection margin positive and 3 patients(8.3%) with the resection margin undetermined respectively. In 2 patients (2.6%) with the resection margin clear. Recurrence CIN occurred in 1 patient (4.8%) with the resection margin positive and 2 patients (5.6%) with the resection margin undetermined respectively, none of the patients (0.0%) with the resection margin clear. The overall cure rate in this study was 93.3% after first LEEP done. The residual CIN was identified in 6 (4.4%) patients. The recurrence CIN occurred in 3 (2.2%) patients. Complications of LEEP occurred in 14.1% (19/135) patients in this study.

CONCLUSIONS: LEEP is a kind of effective and safe method for the treatment of cervical intraepithelial neoplasia. The status of resection margin should be concerned. Margin involvement of specimen is the risk factor for residual and recurrence of CIN.

Pub Med

Leep Procedure - Studies and Links

LEEP Procedure Excision procedure (LEEP) increasingly is being used for the treatment of cervical intraepithelial neoplasia (CIN).

Good Things Still Come in Old Packages: Cryosurgery vs LEEP has been confirmed in numerous previous studies of large the patient to a conization procedure should there us would probably proceed to a LEEP procedure.

Information on LEEP, Colposcopy Unit, Sunnybrook Please click here for detailed Post Leep Instructions. There are no long-term studies that have specifically evaluated this procedure.

Geocrawler.com - mozilla-performance - WOMEN'S HEALTH TODAY - Investigate clinical research studies for osteoporosis and find studies based on womenshealth.about.com/library/weekly/aa020801a.htm.

IMRT Case Studies: May 2003 The following case studies demonstrate how IMRT can work for patients for whom CASE 1: A 65-year-old white female underwent a LEEP procedure.

Carcinoma insitu of the cervix - CIN 3 in following up after the procedure with adequate was performed (39% adequate visualization) versus LEEP (71% adequate go back to some older studies)

Loop Electrosurgical Excisional Procedure (LEEP) Clinical Loop Electrosurgical Excision Procedure (LEEP) for Treating Miscellaneous LEEP Clinical Resources: Health Reviews for Library and Information Studies.

LEEP History and Principles 2. Later large scale studies demonstrated that prophylactic electrocautery prevented still in use, Loop Electrosurgical Excisional Procedure (LEEP).

Leep Procedure - Links

The LEEP Procedure 2002 The LEEP Procedure. Patient Information. As with any surgical procedure, some complications may occur following the LEEP procedure.

LOOP ELECTROSURGICAL EXCISION PROCEDURE (LEEP)- 1996 The LEEP procedure recently has been introduced into the United States, and represents a major advance in the treatment of pre-cancerous lesions of the cervix.

"LEEP" procedure LEEP PROCEDURE. What is it? Cervical How is a LEEP procedure performed? A speculum is placed in the vagina just like for a PAP smear.

The LEEP Procedure The LEEP Procedure. What is it? Although pronounced "leap," the procedure is actually LEEP, or loop electrosurgical excision procedure.

LEEP Procedure - What is LEEP? - Loop Electrosurgical Excision Advertisement. LEEP Procedure. What is the LEEP procedure? by Tracee Cornforth. The loop LEEP. What happens during the LEEP procedure?

Loop Electrosurgical Excision Procedure (LEEP) | Questions about Frequently Asked Questions about the LEEP procedure for diagnosing cervical cancer. What is a Loop Electrosurgical Excision Procedure (LEEP) procedure like?

LEEP Procedure Health Science Report by Joe Glickman Jr MD. LEEP Procedure. The failure rate of the LEEP procedure for treatment of CIN-3 was evaluated over a 5-year period.

Lahey Clinic | Gynecology Leep Procedure Leep Procedure. What is it? The LEEP Procedure, otherwise known as Loop Electrosurgical Excision Procedure, removes abnormal tissue/cells from your cervix.